CMap Candidate Details
Structure:
| CMap ID: | C00947 |
| Pert ID: | BRD-K09900591 |
| Compound Name: | caffeic-acid |
| Targets: | ALOX5|MIF |
| MoA: | HIV integrase inhibitor; lipoxygenase inhibitor; nitric oxide production inhibitor; tumor necrosis factor production inhibitor |
| SMILES: | OC(=O)\C=C\c1ccc(O)c(O)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49808 | BRD-K09900591 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50150 | BRD-K09900591 | HA1E | 10 uM | 6 h | 0.23 | 0.96 | 0.07 | 0.0 | 0.0 | 0.0 |
| 50502 | BRD-K09900591 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.97 | 0.45 |
| 50652 | BRD-K09900591 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50909 | BRD-K09900591 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51127 | BRD-K09900591 | VCAP | 10 uM | 6 h | 0.19 | 0.81 | 0.0 | 0.0 | 0.0 | 0.0 |
| 53005 | BRD-K09900591 | HEPG2 | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 53067 | BRD-K09900591 | MCF10A | 100 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.15 | 1.07 |