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CMap Candidate Details

Structure:
CMap ID: C00977
Pert ID: BRD-K44849676
Compound Name: capsazepine
Targets: TRPV1|TRPV4
MoA: TRPV agonist
SMILES: Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3028 BRD-K44849676 HA1E 10 uM 6 h 0.0 0.0 0.0 0.25 0.87 0.18
3205 BRD-K44849676 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.29
3508 BRD-K44849676 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3804 BRD-K44849676 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44401 BRD-K44849676 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44708 BRD-K44849676 A549 10 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.12
44967 BRD-K44849676 ASC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
45262 BRD-K44849676 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45530 BRD-K44849676 HT29 10 uM 6 h -0.26 -1.07 0.28 -0.31 -1.04 0.66
45824 BRD-K44849676 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.22
46082 BRD-K44849676 NPC 10 uM 24 h 0.0 0.0 0.0 0.21 0.76 0.05
46720 BRD-K44849676 SKB 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
99551 BRD-K44849676 U2OS 12.5 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.56
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).