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CMap Candidate Details

Structure:
CMap ID: C00101
Pert ID: BRD-K32318651
Compound Name: acyclovir
Targets: PNP
MoA: DNA polymerase inhibitor
SMILES: Nc1nc2n(COCCO)cnc2c(=O)[nH]1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19012 BRD-K32318651 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19443 BRD-K32318651 A549 10 uM 6 h 0.18 0.77 0.0 0.0 0.0 0.0
19985 BRD-K32318651 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20316 BRD-K32318651 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.4
20640 BRD-K32318651 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20890 BRD-K32318651 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21736 BRD-K32318651 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.18 1.14
91312 BRD-K32318651 HUH7 15 uM 72 h 0.35 1.47 1.12 0.29 1.02 0.48
121758 BRD-K32318651 HELA 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
129785 BRD-K32318651 HA1E 0.74 uM 24 h 0.26 1.08 0.21 -0.27 -0.92 0.32
129819 BRD-K32318651 HEK293 2.22 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
129912 BRD-K32318651 JURKAT 0.03 uM 24 h -0.32 -1.32 0.85 0.24 0.86 0.16
129946 BRD-K32318651 MCF10A 2.22 uM 24 h 0.28 1.19 0.41 0.29 1.03 0.51
130030 BRD-K32318651 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130078 BRD-K32318651 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130102 BRD-K32318651 THP1 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130151 BRD-K32318651 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).