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CMap Candidate Details

Structure:
CMap ID: C01019
Pert ID: BRD-A17411484
Compound Name: carprofen
Targets: PTGS1|PTGS2
MoA: cyclooxygenase inhibitor
SMILES: CC(C(O)=O)c1ccc2c(c1)[nH]c1ccc(Cl)cc21
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4280 BRD-A17411484 HCC515 10 uM 24 h 0.17 0.69 0.0 0.0 0.0 0.0
4981 BRD-A17411484 VCAP 10 uM 6 h -0.24 -1.02 0.17 -0.31 -1.05 0.7
37450 BRD-A17411484 ASC 10 uM 24 h 0.23 0.96 0.07 -0.33 -1.11 0.91
37790 BRD-A17411484 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38301 BRD-A17411484 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
38605 BRD-A17411484 PHH 10 uM 24 h 0.23 0.96 0.08 -0.33 -1.1 0.88
120285 BRD-A17411484 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120346 BRD-A17411484 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120380 BRD-A17411484 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120410 BRD-A17411484 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120442 BRD-A17411484 PC3 1.11 uM 24 h -0.25 -1.04 0.21 0.0 0.0 0.0
120481 BRD-A17411484 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128890 BRD-A17411484 A375 2.22 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
128906 BRD-A17411484 HA1E 2.22 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).