CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01051
Pert ID:	BRD-K65503129
Compound Name:	CCT018159
Targets:	HSP90AA1\|HSP90AB1
MoA:	HSP inhibitor
SMILES:	CCc1cc(-c2n[nH]c(C)c2-c2ccc3OCCOc3c2)c(O)cc1O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4232	BRD-K65503129	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
4460	BRD-K65503129	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4704	BRD-K65503129	PC3	10 uM	24 h	-0.23	-0.95	0.08	0.0	0.0	0.0
5106	BRD-K65503129	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.31	-1.05	0.7
44429	BRD-K65503129	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44605	BRD-K65503129	A549	10 uM	24 h	0.0	0.0	0.0	0.38	1.34	1.72
45004	BRD-K65503129	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45295	BRD-K65503129	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45558	BRD-K65503129	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45839	BRD-K65503129	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
46117	BRD-K65503129	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46432	BRD-K65503129	PHH	10 uM	24 h	-0.31	-1.3	0.82	-0.42	-1.42	2.02
46757	BRD-K65503129	SKB	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.16	1.11
99342	BRD-K65503129	U2OS	10 uM	6 h	-0.25	-1.05	0.23	0.0	0.0	0.0

Summary