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CMap Candidate Details

Structure:
CMap ID: C00107
Pert ID: BRD-K00152668
Compound Name: adarotene
Targets: RARB|RARG
MoA: retinoid receptor agonist
SMILES: OC(=O)\C=C\c1ccc(cc1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122828 BRD-K00152668 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122872 BRD-K00152668 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122926 BRD-K00152668 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122957 BRD-K00152668 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122997 BRD-K00152668 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123086 BRD-K00152668 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.34
123139 BRD-K00152668 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123158 BRD-K00152668 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123210 BRD-K00152668 YAPC 0.37 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
131224 BRD-K00152668 A549 0.74 uM 24 h -0.22 -0.92 0.06 -0.27 -0.89 0.27
131267 BRD-K00152668 HA1E 0.25 uM 24 h 0.25 1.05 0.16 0.24 0.86 0.16
131334 BRD-K00152668 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131387 BRD-K00152668 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.11
131421 BRD-K00152668 MCF??7.00 2.22 uM 24 h 0.16 0.68 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).