CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01079
Pert ID:	BRD-K71059170
Compound Name:	cefixime
Targets:
MoA:	bacterial cell wall synthesis inhibitor
SMILES:	Nc1nc(cs1)C(=N\OCC(O)=O)\C(=O)N[C@H]1[C@H]2SCC(C=C)=C(N2C1=O)C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4246	BRD-K71059170	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
4593	BRD-K71059170	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
4715	BRD-K71059170	PC3	10 uM	24 h	-0.17	-0.72	0.0	-0.19	-0.63	0.01
5119	BRD-K71059170	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.18	-0.6	0.0
39170	BRD-K71059170	A375	10 uM	6 h	-0.25	-1.03	0.19	-0.28	-0.95	0.41
39484	BRD-K71059170	A549	10 uM	6 h	0.0	0.0	0.0	0.21	0.75	0.04
39756	BRD-K71059170	ASC	10 uM	24 h	0.2	0.83	0.0	-0.21	-0.71	0.03
40049	BRD-K71059170	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40316	BRD-K71059170	HT29	10 uM	6 h	0.0	0.0	0.0	-0.29	-0.99	0.5
40634	BRD-K71059170	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40858	BRD-K71059170	NEU	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.39
41174	BRD-K71059170	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41512	BRD-K71059170	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99413	BRD-K71059170	U2OS	4 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary