CMap Candidate Details
Structure:
| CMap ID: | C00108 |
| Pert ID: | BRD-K67789209 |
| Compound Name: | adatanserin |
| Targets: | HTR1A|HTR2A |
| MoA: | serotonin receptor agonist; serotonin receptor antagonist |
| SMILES: | O=C(NCCN1CCN(CC1)c1ncccn1)C12CC3CC(CC(C3)C1)C2 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 126384 | BRD-K67789209 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126448 | BRD-K67789209 | HEK293 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126480 | BRD-K67789209 | HELA | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126498 | BRD-K67789209 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.06 | 0.72 |
| 126526 | BRD-K67789209 | MCF10A | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.17 | 0.95 |
| 126541 | BRD-K67789209 | MCF??7.00 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126558 | BRD-K67789209 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126582 | BRD-K67789209 | PC3 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126610 | BRD-K67789209 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.32 | 1.71 |
| 134356 | BRD-K67789209 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.22 |
| 134407 | BRD-K67789209 | HA1E | 0.74 uM | 24 h | -0.25 | -1.04 | 0.22 | 0.0 | 0.0 | 0.0 |
| 134515 | BRD-K67789209 | HUVEC | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |