CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01089
Pert ID:	BRD-A78723049
Compound Name:	cefotetan
Targets:
MoA:	bacterial cell wall synthesis inhibitor
SMILES:	CO[C@]1(NC(=O)C2SC(S2)=C(C(N)=O)C(O)=O)C2SCC(CSc3nnnn3C)=C(N2C1=O)C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95453	BRD-A78723049	U2OS	0.12 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
127035	BRD-A78723049	A375	0.04 uM	24 h	0.0	0.0	0.0	-0.26	-0.88	0.25
127055	BRD-A78723049	HA1E	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127121	BRD-A78723049	HELA	0.04 uM	24 h	-0.24	-1.01	0.16	0.0	0.0	0.0
127155	BRD-A78723049	HT29	3.33 uM	24 h	0.0	0.0	0.0	0.25	0.9	0.21
127221	BRD-A78723049	MCF??7.00	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127257	BRD-A78723049	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.34
127296	BRD-A78723049	THP1	0.04 uM	24 h	0.0	0.0	0.0	-0.37	-1.23	1.28
135063	BRD-A78723049	A549	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135119	BRD-A78723049	HEK293	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135189	BRD-A78723049	JURKAT	0.01 uM	24 h	0.0	0.0	0.0	0.29	1.02	0.47
135222	BRD-A78723049	MCF10A	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135289	BRD-A78723049	MDAMB231	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135336	BRD-A78723049	YAPC	0.01 uM	24 h	-0.17	-0.73	0.0	0.0	0.0	0.0

Summary