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CMap Candidate Details

Structure:
CMap ID: C01108
Pert ID: BRD-K02637541
Compound Name: celecoxib
Targets: CA12|PDPK1|PTGS2
MoA: cyclooxygenase inhibitor
SMILES: Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5875 BRD-K02637541 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21703 BRD-K02637541 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.81
37578 BRD-K02637541 ASC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.26
91115 BRD-K02637541 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
98792 BRD-K02637541 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98991 BRD-K02637541 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99972 BRD-K02637541 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
115266 BRD-K02637541 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115312 BRD-K02637541 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115359 BRD-K02637541 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115407 BRD-K02637541 HCC515 10 uM 24 h -0.29 -1.2 0.57 0.0 0.0 0.0
115510 BRD-K02637541 HT29 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
115560 BRD-K02637541 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.11
122908 BRD-K02637541 HEK293 0.125 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.55
122946 BRD-K02637541 HELA 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.76
123033 BRD-K02637541 JURKAT 0.37 uM 24 h 0.23 0.96 0.08 -0.35 -1.17 1.13
123123 BRD-K02637541 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123195 BRD-K02637541 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131371 BRD-K02637541 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.18 0.64 0.0
131408 BRD-K02637541 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
131470 BRD-K02637541 PC3 0.74 uM 24 h -0.21 -0.89 0.04 0.33 1.17 0.93
131508 BRD-K02637541 YAPC 0.74 uM 24 h -0.28 -1.19 0.51 -0.27 -0.91 0.3
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).