CMap Candidate Details
Structure:
| CMap ID: | C01120 |
| Pert ID: | BRD-K96194081 |
| Compound Name: | cepharanthine |
| Targets: | |
| MoA: | NFkB pathway inhibitor |
| SMILES: | COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(Oc5c6OCOc6cc6CCN(C)[C@@H](Cc7ccc(Oc1c2)cc7)c56)cc34 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 127344 | BRD-K96194081 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127386 | BRD-K96194081 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.07 | 0.63 |
| 127418 | BRD-K96194081 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127486 | BRD-K96194081 | HT29 | 3.33 uM | 24 h | -0.19 | -0.79 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127506 | BRD-K96194081 | JURKAT | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127552 | BRD-K96194081 | MCF10A | 10 uM | 24 h | -0.28 | -1.19 | 0.51 | 0.28 | 0.97 | 0.36 |
| 127571 | BRD-K96194081 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127599 | BRD-K96194081 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127641 | BRD-K96194081 | THP1 | 10 uM | 24 h | 0.26 | 1.09 | 0.23 | 0.0 | 0.0 | 0.0 |
| 127676 | BRD-K96194081 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135365 | BRD-K96194081 | HELA | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |