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CMap Candidate Details

Structure:
CMap ID: C01124
Pert ID: BRD-K52075040
Compound Name: cerulenin
Targets: FASN
MoA: fatty acid synthase inhibitor
SMILES: C\C=C\C\C=C\CCC(=O)[C@H]1O[C@H]1C(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8951 BRD-K52075040 A375 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9439 BRD-K52075040 AGS 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9742 BRD-K52075040 H1299 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10269 BRD-K52075040 HCC515 40 uM 6 h -0.27 -1.1 0.36 0.0 0.0 0.0
10532 BRD-K52075040 HCT116 40 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
10796 BRD-K52075040 HEPG2 40 uM 6 h 0.0 0.0 0.0 0.22 0.76 0.05
10980 BRD-K52075040 HT29 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11281 BRD-K52075040 MCF??7.00 40 uM 6 h 0.2 0.84 0.0 0.0 0.0 0.0
11504 BRD-K52075040 NCIH2073 40 uM 6 h -0.22 -0.91 0.05 0.0 0.0 0.0
11778 BRD-K52075040 NCIH508 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12065 BRD-K52075040 NCIH596 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12453 BRD-K52075040 PC3 40 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
12805 BRD-K52075040 SW480 40 uM 6 h -0.23 -0.95 0.09 0.27 0.96 0.33
12958 BRD-K52075040 THP1 40 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.68
13289 BRD-K52075040 U937 40 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.23
13480 BRD-K52075040 VCAP 40 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
98525 BRD-K52075040 NEU 10 uM 6 h -0.29 -1.22 0.62 0.0 0.0 0.0
98615 BRD-K52075040 NPC 10 uM 24 h 0.26 1.09 0.22 -0.33 -1.11 0.92
118441 BRD-K52075040 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118475 BRD-K52075040 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).