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CMap Candidate Details

Structure:
CMap ID: C01131
Pert ID: BRD-M98279124
Compound Name: cevimeline
Targets: CHRM1|CHRM3
MoA: acetylcholine receptor agonist
SMILES: C[C@H]1O[C@]2(CS1)CN1CCC2CC1.C[C@@H]1O[C@@]2(CS1)CN1CCC2CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121741 BRD-M98279124 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121773 BRD-M98279124 HELA 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
121850 BRD-M98279124 PC3 1.11 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.77
129768 BRD-M98279124 A375 0.25 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
129845 BRD-M98279124 HEK293 0.08 uM 24 h -0.19 -0.81 0.0 0.32 1.15 0.88
129901 BRD-M98279124 HT29 0.01 uM 24 h -0.26 -1.07 0.27 -0.28 -0.93 0.34
129971 BRD-M98279124 MCF10A 2.22 uM 24 h -0.21 -0.86 0.02 0.27 0.95 0.31
130009 BRD-M98279124 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130056 BRD-M98279124 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130127 BRD-M98279124 THP1 0.25 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
130170 BRD-M98279124 YAPC 0.03 uM 24 h 0.23 0.95 0.07 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).