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CMap Candidate Details

Structure:
CMap ID: C01145
Pert ID: BRD-A35623999
Compound Name: CGP-37157
Targets: SLC8A1
MoA: mitochondrial Na+/Ca2+ exchanger antagonist; sodium/calcium exchange inhibitor
SMILES: Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2803 BRD-A35623999 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3100 BRD-A35623999 HCC515 10 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
3437 BRD-A35623999 PC3 10 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
3679 BRD-A35623999 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39044 BRD-A35623999 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39394 BRD-A35623999 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39565 BRD-A35623999 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39891 BRD-A35623999 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40175 BRD-A35623999 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40566 BRD-A35623999 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40693 BRD-A35623999 NEU 10 uM 24 h 0.26 1.07 0.19 -0.26 -0.87 0.23
40990 BRD-A35623999 NPC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
41314 BRD-A35623999 SKB 10 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.99
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).