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CMap Candidate Details

Structure:
CMap ID: C01147
Pert ID: BRD-K13087974
Compound Name: CGP-52411
Targets: EGFR
MoA: EGFR inhibitor
SMILES: O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33534 BRD-K13087974 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34316 BRD-K13087974 HA1E 10 uM 6 h 0.28 1.16 0.36 -0.24 -0.81 0.14
34562 BRD-K13087974 HCC515 10 uM 6 h 0.25 1.06 0.19 0.0 0.0 0.0
34831 BRD-K13087974 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.22
35097 BRD-K13087974 HT29 10 uM 6 h 0.0 0.0 0.0 0.33 1.16 0.9
35296 BRD-K13087974 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.26
35542 BRD-K13087974 NEU 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.4
35733 BRD-K13087974 NPC 10 uM 24 h -0.18 -0.73 0.0 0.0 0.0 0.0
35934 BRD-K13087974 PC3 10 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
36207 BRD-K13087974 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36500 BRD-K13087974 SKB 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
36779 BRD-K13087974 VCAP 10 uM 24 h 0.31 1.31 0.76 -0.31 -1.04 0.67
96115 BRD-K13087974 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).