CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01148
Pert ID:	BRD-K32292990
Compound Name:	CGP-53353
Targets:	EGFR\|PRKCB
MoA:	EGFR inhibitor; PKC inhibitor
SMILES:	Fc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccc(F)cc2)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2862	BRD-K32292990	HA1E	10 uM	24 h	-0.22	-0.9	0.04	-0.44	-1.48	15.35
3174	BRD-K32292990	HCC515	10 uM	24 h	-0.23	-0.97	0.1	0.28	1.01	0.44
3482	BRD-K32292990	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3951	BRD-K32292990	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.3	-1.02	0.6
44364	BRD-K32292990	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44561	BRD-K32292990	A549	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.97	0.45
44923	BRD-K32292990	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45493	BRD-K32292990	HT29	10 uM	6 h	0.19	0.8	0.0	0.44	1.56	2.33
45681	BRD-K32292990	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.35
46041	BRD-K32292990	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46677	BRD-K32292990	SKB	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.08	0.79
53442	BRD-K32292990	HEPG2	10 uM	6 h	-0.25	-1.03	0.2	0.0	0.0	0.0
53574	BRD-K32292990	HUH7	10 uM	6 h	0.0	0.0	0.0	-0.35	-1.17	1.12
53652	BRD-K32292990	PHH	2.5 uM	24 h	-0.21	-0.87	0.02	0.0	0.0	0.0

Summary