CMap Candidate Details
Structure:
| CMap ID: | C01151 |
| Pert ID: | BRD-K42500029 |
| Compound Name: | CGP-57380 |
| Targets: | AURKB|LCK|MKNK1|MKNK2|SGK1 |
| MoA: | MAP kinase inhibitor |
| SMILES: | Nc1ncnc2[nH]nc(Nc3ccc(F)cc3)c12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 5330 | BRD-K42500029 | HA1E | 10 uM | 24 h | 0.3 | 1.25 | 0.56 | 0.0 | 0.0 | 0.0 |
| 5630 | BRD-K42500029 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5914 | BRD-K42500029 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.23 |
| 6096 | BRD-K42500029 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.04 | 0.56 |
| 6279 | BRD-K42500029 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6548 | BRD-K42500029 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37157 | BRD-K42500029 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.4 |
| 37657 | BRD-K42500029 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38083 | BRD-K42500029 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.07 | 0.61 |
| 38482 | BRD-K42500029 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38722 | BRD-K42500029 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.09 | 0.84 |
| 38955 | BRD-K42500029 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96144 | BRD-K42500029 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 99528 | BRD-K42500029 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |