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CMap Candidate Details

Structure:
CMap ID: C01152
Pert ID: BRD-K79090631
Compound Name: CGP-60474
Targets: CDK1|CDK2
MoA: CDK inhibitor
SMILES: OCCCNc1cc(ccn1)-c1ccnc(Nc2cccc(Cl)c2)n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29948 BRD-K79090631 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33139 BRD-K79090631 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33506 BRD-K79090631 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91554 BRD-K79090631 BT20 0.37 uM 6 h 0.0 0.0 0.0 0.37 1.31 1.59
92062 BRD-K79090631 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92093 BRD-K79090631 HCC515 0.12 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
92131 BRD-K79090631 HS578T 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92185 BRD-K79090631 HT29 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92211 BRD-K79090631 MCF10A 0.04 uM 24 h 0.25 1.06 0.19 0.27 0.96 0.33
92272 BRD-K79090631 MCF??7.00 1.11 uM 3 h 0.0 0.0 0.0 0.29 1.04 0.54
92334 BRD-K79090631 PC3 0.04 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
92363 BRD-K79090631 SKBR3 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92665 BRD-K79090631 LNCAP 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92978 BRD-K79090631 CD34 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93155 BRD-K79090631 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93261 BRD-K79090631 JURKAT 0.12 uM 24 h 0.18 0.76 0.0 0.29 1.02 0.49
93346 BRD-K79090631 MDAMB231 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93532 BRD-K79090631 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93573 BRD-K79090631 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93680 BRD-K79090631 ASC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93824 BRD-K79090631 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93953 BRD-K79090631 HUVEC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94170 BRD-K79090631 NPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94221 BRD-K79090631 SHSY5Y 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94438 BRD-K79090631 A549 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94677 BRD-K79090631 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94726 BRD-K79090631 HME1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95197 BRD-K79090631 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).