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CMap Candidate Details

Structure:
CMap ID: C01173
Pert ID: BRD-K29458283
Compound Name: chlorambucil
Targets:
MoA: DNA inhibitor
SMILES: OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5603 BRD-K29458283 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
5897 BRD-K29458283 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37629 BRD-K29458283 ASC 10 uM 24 h -0.23 -0.95 0.09 -0.34 -1.16 1.11
38456 BRD-K29458283 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38705 BRD-K29458283 PHH 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
51022 BRD-K29458283 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52026 BRD-K29458283 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52282 BRD-K29458283 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91438 BRD-K29458283 HUH7 10 uM 72 h 0.0 0.0 0.0 -0.25 -0.84 0.17
121889 BRD-K29458283 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121915 BRD-K29458283 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122041 BRD-K29458283 HUVEC 10 uM 24 h 0.24 1.0 0.1 0.0 0.0 0.0
122136 BRD-K29458283 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122187 BRD-K29458283 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122215 BRD-K29458283 YAPC 10 uM 24 h 0.33 1.39 1.02 0.0 0.0 0.0
130221 BRD-K29458283 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130253 BRD-K29458283 HEK293 2.22 uM 24 h 0.2 0.84 0.0 -0.19 -0.65 0.01
130283 BRD-K29458283 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130315 BRD-K29458283 HT29 0.01 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
130392 BRD-K29458283 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).