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CMap Candidate Details

Structure:
CMap ID: C01185
Pert ID: BRD-A01593789
Compound Name: chlormadinone-acetate
Targets: PGR
MoA: 5 alpha reductase inhibitor
SMILES: CC(=O)O[C@@]1(CCC2C3C=C(Cl)C4=CC(=O)CC[C@]4(C)C3CC[C@]12C)C(C)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5384 BRD-A01593789 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.76 0.07
5708 BRD-A01593789 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5968 BRD-A01593789 HT29 10 uM 6 h -0.31 -1.29 0.79 0.0 0.0 0.0
6443 BRD-A01593789 VCAP 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.37
37320 BRD-A01593789 A549 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.21 1.24
37424 BRD-A01593789 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37777 BRD-A01593789 HEPG2 10 uM 6 h -0.3 -1.26 0.72 -0.35 -1.18 1.14
38121 BRD-A01593789 MCF??7.00 10 uM 24 h 0.19 0.78 0.0 0.0 0.0 0.0
38278 BRD-A01593789 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38590 BRD-A01593789 PHH 10 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
38807 BRD-A01593789 SKB 10 uM 24 h 0.29 1.21 0.45 0.0 0.0 0.0
96737 BRD-A01593789 A375 10 uM 24 h 0.28 1.17 0.36 0.0 0.0 0.0
96788 BRD-A01593789 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).