CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01203
Pert ID:	BRD-A04553218
Compound Name:	chlorphenamine
Targets:	HRH1\|SLC6A2\|SLC6A3\|SLC6A4
MoA:	histamine receptor antagonist
SMILES:	CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5487	BRD-A04553218	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
25463	BRD-A04553218	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37430	BRD-A04553218	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38284	BRD-A04553218	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38594	BRD-A04553218	PHH	10 uM	24 h	-0.29	-1.21	0.58	-0.27	-0.92	0.32
38811	BRD-A04553218	SKB	10 uM	24 h	0.28	1.16	0.34	0.0	0.0	0.0
52877	BRD-A04553218	HEPG2	40 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
53170	BRD-A04553218	MCF10A	100 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91440	BRD-A04553218	HUH7	12 uM	72 h	0.27	1.14	0.32	0.27	0.95	0.32
122533	BRD-A04553218	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122565	BRD-A04553218	A549	10 uM	24 h	0.0	0.0	0.0	-0.38	-1.29	1.56
122593	BRD-A04553218	HA1E	10 uM	24 h	0.28	1.17	0.36	-0.22	-0.73	0.05
122621	BRD-A04553218	HEK293	10 uM	24 h	0.26	1.08	0.22	0.0	0.0	0.0
122670	BRD-A04553218	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122783	BRD-A04553218	PC3	10 uM	24 h	0.0	0.0	0.0	-0.27	-0.9	0.29
130951	BRD-A04553218	HELA	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131021	BRD-A04553218	HUVEC	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131074	BRD-A04553218	MCF??7.00	2.22 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.41
131106	BRD-A04553218	MDAMB231	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131170	BRD-A04553218	YAPC	2.22 uM	24 h	-0.23	-0.96	0.1	0.0	0.0	0.0

Summary