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CMap Candidate Details

Structure:
CMap ID: C01207
Pert ID: BRD-K89997465
Compound Name: chlorpromazine
Targets: ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|CALM1|CHRM1|CHRM3|DRD1|DRD2|DRD3|DRD4|DRD5|HRH1|HRH4|HTR1A|HTR2A|HTR2B|HTR2C|HTR6|HTR7|KCNH2|ORM1|ORM2|SMPD1|TRPC5
MoA: dopamine receptor antagonist
SMILES: CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1459 BRD-K89997465 NPC 12.5 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.17
5236 BRD-K89997465 A375 10 uM 6 h -0.28 -1.16 0.46 0.0 0.0 0.0
5372 BRD-K89997465 HA1E 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
5694 BRD-K89997465 HCC515 10 uM 24 h -0.25 -1.05 0.23 0.41 1.43 2.21
6224 BRD-K89997465 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6599 BRD-K89997465 VCAP 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.42
42156 BRD-K89997465 A549 10 uM 6 h 0.24 1.0 0.11 0.0 0.0 0.0
42493 BRD-K89997465 ASC 10 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.13
42803 BRD-K89997465 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.43 1.52 2.29
43246 BRD-K89997465 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43969 BRD-K89997465 PHH 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
44218 BRD-K89997465 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90946 BRD-K89997465 HUH7 10 uM 72 h 0.0 0.0 0.0 0.34 1.22 1.15
98515 BRD-K89997465 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127857 BRD-K89997465 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127898 BRD-K89997465 HT29 10 uM 24 h -0.28 -1.15 0.44 -0.27 -0.92 0.33
127931 BRD-K89997465 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127985 BRD-K89997465 MCF10A 3.33 uM 24 h 0.24 0.99 0.1 -0.28 -0.95 0.41
135558 BRD-K89997465 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.39 1.39 2.17
135649 BRD-K89997465 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135739 BRD-K89997465 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).