CMap Candidate Details
Structure:
| CMap ID: | C01208 |
| Pert ID: | BRD-K97746869 |
| Compound Name: | chlorpropamide |
| Targets: | ABCC8|KCNJ10|KCNJ11 |
| MoA: | ATP channel blocker |
| SMILES: | CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 52992 | BRD-K97746869 | HEPG2 | 40 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96293 | BRD-K97746869 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127380 | BRD-K97746869 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.69 | 0.02 |
| 127408 | BRD-K97746869 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127483 | BRD-K97746869 | HT29 | 10 uM | 24 h | 0.31 | 1.29 | 0.67 | 0.0 | 0.0 | 0.0 |
| 127495 | BRD-K97746869 | JURKAT | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.19 | 1.16 |
| 127589 | BRD-K97746869 | PC3 | 10 uM | 24 h | 0.3 | 1.23 | 0.5 | 0.0 | 0.0 | 0.0 |
| 127665 | BRD-K97746869 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.96 | 0.34 |
| 135357 | BRD-K97746869 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135427 | BRD-K97746869 | MCF10A | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135461 | BRD-K97746869 | MCF??7.00 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.84 | 0.17 |
| 135490 | BRD-K97746869 | THP1 | 0.01 uM | 24 h | -0.19 | -0.78 | 0.0 | 0.0 | 0.0 | 0.0 |