CMap Candidate Details
Structure:
| CMap ID: | C01226 |
| Pert ID: | BRD-K22861715 |
| Compound Name: | chrysin |
| Targets: | AKR1B1|CDK6|CYP19A1|CYP1B1 |
| MoA: | breast cancer resistance protein inhibitor |
| SMILES: | Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 99755 | BRD-K22861715 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121390 | BRD-K22861715 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.04 | 0.65 |
| 121420 | BRD-K22861715 | HELA | 10 uM | 24 h | 0.24 | 1.01 | 0.12 | 0.0 | 0.0 | 0.0 |
| 121485 | BRD-K22861715 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121533 | BRD-K22861715 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129415 | BRD-K22861715 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129501 | BRD-K22861715 | HT29 | 0.25 uM | 24 h | -0.28 | -1.17 | 0.48 | -0.33 | -1.11 | 0.92 |
| 129532 | BRD-K22861715 | MCF??7.00 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.45 |