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CMap Candidate Details

Structure:
CMap ID: C01234
Pert ID: BRD-K67680372
Compound Name: CI-966
Targets: SLC6A1
MoA: GAT inhibitor
SMILES: OC(=O)C1=CCCN(CCOC(c2ccc(cc2)C(F)(F)F)c2ccc(cc2)C(F)(F)F)C1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4465 BRD-K67680372 HCC515 10 uM 24 h -0.22 -0.91 0.05 -0.29 -0.97 0.45
5110 BRD-K67680372 VCAP 10 uM 6 h 0.0 0.0 0.0 0.45 1.58 2.35
39744 BRD-K67680372 ASC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.81
40038 BRD-K67680372 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.16
40850 BRD-K67680372 NEU 10 uM 24 h -0.3 -1.25 0.69 -0.31 -1.03 0.63
41161 BRD-K67680372 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41499 BRD-K67680372 SKB 10 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
99373 BRD-K67680372 U2OS 10 uM 6 h -0.27 -1.14 0.42 -0.24 -0.81 0.12
124583 BRD-K67680372 A375 10 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
124702 BRD-K67680372 HT29 0.37 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
124808 BRD-K67680372 MDAMB231 0.37 uM 24 h 0.32 1.34 0.89 0.0 0.0 0.0
124851 BRD-K67680372 PC3 1.11 uM 24 h 0.31 1.29 0.66 0.0 0.0 0.0
124893 BRD-K67680372 THP1 0.125 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
132700 BRD-K67680372 A549 0.01 uM 24 h 0.0 0.0 0.0 0.19 0.68 0.01
132729 BRD-K67680372 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132765 BRD-K67680372 HEK293 0.08 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
132795 BRD-K67680372 HELA 0.74 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
132842 BRD-K67680372 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132879 BRD-K67680372 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.19 0.66 0.01
132908 BRD-K67680372 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132964 BRD-K67680372 YAPC 0.08 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).