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CMap Candidate Details

Structure:
CMap ID: C01235
Pert ID: BRD-K88544581
Compound Name: CI-976
Targets: ACAT1|CES1
MoA: ACAT inhibitor
SMILES: CCCCCCCCCCC(C)(C)C(=O)Nc1c(OC)cc(OC)cc1OC
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9250 BRD-K88544581 A549 80 uM 6 h 0.0 0.0 0.0 -0.54 -1.81 15.65
9534 BRD-K88544581 AGS 80 uM 6 h 0.0 0.0 0.0 -0.36 -1.21 1.24
9840 BRD-K88544581 H1299 80 uM 6 h 0.0 0.0 0.0 -0.36 -1.21 1.24
10091 BRD-K88544581 HA1E 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10617 BRD-K88544581 HCT116 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11030 BRD-K88544581 HT29 80 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
12159 BRD-K88544581 NCIH596 80 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.15
12429 BRD-K88544581 PC3 80 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.36
12890 BRD-K88544581 SW480 80 uM 6 h 0.25 1.06 0.19 0.35 1.25 1.29
13383 BRD-K88544581 U937 80 uM 6 h 0.0 0.0 0.0 0.4 1.4 2.18
13697 BRD-K88544581 VCAP 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
116286 BRD-K88544581 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116415 BRD-K88544581 HCC515 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116468 BRD-K88544581 HEPG2 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116565 BRD-K88544581 MCF??7.00 0.04 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
127509 BRD-K88544581 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.35
127679 BRD-K88544581 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135367 BRD-K88544581 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
135434 BRD-K88544581 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135495 BRD-K88544581 THP1 0.03 uM 24 h -0.3 -1.25 0.71 -0.42 -1.42 2.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).