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CMap Candidate Details

Structure:
CMap ID: C01237
Pert ID: BRD-K58736316
Compound Name: cianidanol
Targets: PTGS1
MoA: fatty acid synthase inhibitor
SMILES: O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123804 BRD-K58736316 A375 3.33 uM 24 h -0.2 -0.82 0.0 0.23 0.8 0.08
123844 BRD-K58736316 A549 10 uM 24 h 0.2 0.82 0.0 -0.34 -1.14 1.01
123910 BRD-K58736316 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123949 BRD-K58736316 HELA 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
124011 BRD-K58736316 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.11
124064 BRD-K58736316 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124132 BRD-K58736316 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124193 BRD-K58736316 THP1 10 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
124245 BRD-K58736316 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132170 BRD-K58736316 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132234 BRD-K58736316 HT29 0.25 uM 24 h 0.26 1.1 0.24 0.3 1.07 0.63
132258 BRD-K58736316 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.85
132302 BRD-K58736316 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.33 1.15 0.9
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).