CMap Candidate Details
Structure:
| CMap ID: | C01239 |
| Pert ID: | BRD-K35245662 |
| Compound Name: | ciclesonide |
| Targets: | NR3C1|SERPINA6 |
| MoA: | glucocorticoid receptor agonist |
| SMILES: | CC(C)C(=O)OCC(=O)[C@@]12O[C@@H](O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120532 | BRD-K35245662 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.42 |
| 120571 | BRD-K35245662 | A549 | 10 uM | 24 h | -0.26 | -1.08 | 0.29 | -0.25 | -0.83 | 0.16 |
| 120628 | BRD-K35245662 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120676 | BRD-K35245662 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.88 | 0.18 |
| 120729 | BRD-K35245662 | JURKAT | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.45 |
| 120787 | BRD-K35245662 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120837 | BRD-K35245662 | YAPC | 10 uM | 24 h | -0.24 | -1.01 | 0.16 | 0.0 | 0.0 | 0.0 |
| 129010 | BRD-K35245662 | HA1E | 2.22 uM | 24 h | -0.23 | -0.96 | 0.1 | 0.0 | 0.0 | 0.0 |
| 129064 | BRD-K35245662 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |