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CMap Candidate Details

Structure:
CMap ID: C01254
Pert ID: BRD-K67017579
Compound Name: cilostazol
Targets: PDE3A|PDE3B
MoA: phosphodiesterase inhibitor
SMILES: O=C1CCc2cc(OCCCCc3nnnn3C3CCCCC3)ccc2N1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5667 BRD-K67017579 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5946 BRD-K67017579 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6365 BRD-K67017579 VCAP 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
37716 BRD-K67017579 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38538 BRD-K67017579 NPC 10 uM 24 h 0.27 1.12 0.26 0.0 0.0 0.0
38762 BRD-K67017579 PHH 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
99360 BRD-K67017579 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124622 BRD-K67017579 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124667 BRD-K67017579 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
124731 BRD-K67017579 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124806 BRD-K67017579 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124848 BRD-K67017579 PC3 10 uM 24 h 0.21 0.88 0.02 -0.2 -0.69 0.02
124890 BRD-K67017579 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132668 BRD-K67017579 A375 0.74 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
132697 BRD-K67017579 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132763 BRD-K67017579 HEK293 0.74 uM 24 h 0.25 1.04 0.14 0.28 0.98 0.37
132815 BRD-K67017579 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132878 BRD-K67017579 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.51
132905 BRD-K67017579 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
132961 BRD-K67017579 YAPC 0.03 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).