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CMap Candidate Details

Structure:
CMap ID: C01259
Pert ID: BRD-K73838513
Compound Name: cinacalcet
Targets: CASR
MoA: calcium channel activator
SMILES: C[C@@H](NCCCc1cccc(c1)C(F)(F)F)c1cccc2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33690 BRD-K73838513 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33834 BRD-K73838513 A549 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.05
34167 BRD-K73838513 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34411 BRD-K73838513 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34673 BRD-K73838513 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34947 BRD-K73838513 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35191 BRD-K73838513 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35462 BRD-K73838513 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35613 BRD-K73838513 NEU 10 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
35831 BRD-K73838513 NPC 10 uM 24 h 0.27 1.12 0.27 0.0 0.0 0.0
36098 BRD-K73838513 PC3 10 uM 6 h 0.31 1.29 0.68 0.23 0.82 0.1
36338 BRD-K73838513 PHH 10 uM 24 h -0.22 -0.9 0.04 0.27 0.96 0.33
36634 BRD-K73838513 SKB 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
36998 BRD-K73838513 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.71 0.03
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).