CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01268
Pert ID:	BRD-K46839850
Compound Name:	cinepazide
Targets:
MoA:	calcium channel activator
SMILES:	COc1cc(cc(OC)c1OC)\C=C\C(=O)N1CCN(CC(=O)N2CCCC2)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125590	BRD-K46839850	A375	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125633	BRD-K46839850	HA1E	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125656	BRD-K46839850	HEK293	0.125 uM	24 h	0.0	0.0	0.0	0.33	1.18	0.98
125743	BRD-K46839850	HUVEC	0.04 uM	24 h	0.0	0.0	0.0	-0.3	-1.02	0.62
125783	BRD-K46839850	JURKAT	1.11 uM	24 h	0.0	0.0	0.0	0.35	1.22	1.19
125804	BRD-K46839850	MCF10A	10 uM	24 h	0.0	0.0	0.0	-0.23	-0.79	0.1
125941	BRD-K46839850	YAPC	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133671	BRD-K46839850	A549	0.03 uM	24 h	0.0	0.0	0.0	-0.31	-1.05	0.7
133773	BRD-K46839850	HELA	0.74 uM	24 h	-0.32	-1.34	0.98	0.0	0.0	0.0
133803	BRD-K46839850	HT29	0.74 uM	24 h	0.25	1.04	0.15	-0.34	-1.16	1.09
133888	BRD-K46839850	MCF??7.00	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133919	BRD-K46839850	MDAMB231	0.74 uM	24 h	0.0	0.0	0.0	-0.38	-1.28	1.45
133949	BRD-K46839850	PC3	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133983	BRD-K46839850	THP1	2.22 uM	24 h	0.33	1.37	0.97	0.3	1.05	0.58

Summary