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CMap Candidate Details

Structure:
CMap ID: C01271
Pert ID: BRD-K07220430
Compound Name: cinnarazine
Targets:
MoA: calcium channel blocker
SMILES: C(\C=C\c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1876 BRD-K07220430 HCC515 10 uM 24 h 0.0 0.0 0.0 0.36 1.29 1.49
2599 BRD-K07220430 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42276 BRD-K07220430 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42612 BRD-K07220430 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43471 BRD-K07220430 NPC 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.3 1.6
43776 BRD-K07220430 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44057 BRD-K07220430 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100021 BRD-K07220430 U2OS 6.66 uM 6 h -0.19 -0.79 0.0 -0.24 -0.8 0.12
122606 BRD-K07220430 HA1E 10 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
122641 BRD-K07220430 HEK293 10 uM 24 h -0.26 -1.09 0.31 0.34 1.21 1.15
122687 BRD-K07220430 HT29 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
122734 BRD-K07220430 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130871 BRD-K07220430 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130891 BRD-K07220430 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130976 BRD-K07220430 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131056 BRD-K07220430 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131091 BRD-K07220430 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131128 BRD-K07220430 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.35 1.22 1.15
131156 BRD-K07220430 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131191 BRD-K07220430 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).