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CMap Candidate Details

Structure:
CMap ID: C01280
Pert ID: BRD-K04804440
Compound Name: ciprofloxacin
Targets: TOP2A
MoA: bacterial DNA gyrase inhibitor
SMILES: OC(=O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90769 BRD-K04804440 HPTEC 320 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91465 BRD-K04804440 HUH7 10 uM 72 h 0.0 0.0 0.0 0.4 1.41 2.18
122564 BRD-K04804440 A549 10 uM 24 h 0.26 1.08 0.21 0.0 0.0 0.0
122620 BRD-K04804440 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122651 BRD-K04804440 HELA 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
122699 BRD-K04804440 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130858 BRD-K04804440 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130900 BRD-K04804440 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130988 BRD-K04804440 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
131020 BRD-K04804440 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131073 BRD-K04804440 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131105 BRD-K04804440 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131139 BRD-K04804440 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131169 BRD-K04804440 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).