CMap Candidate Details
Structure:
| CMap ID: | C01290 |
| Pert ID: | BRD-A12896037 |
| Compound Name: | cisapride |
| Targets: | HTR2A|HTR3A|HTR4|KCNH2 |
| MoA: | serotonin receptor agonist |
| SMILES: | COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122246 | BRD-A12896037 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.09 | 0.68 |
| 122283 | BRD-A12896037 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.39 |
| 122386 | BRD-A12896037 | MCF??7.00 | 10 uM | 24 h | 0.21 | 0.87 | 0.01 | 0.0 | 0.0 | 0.0 |
| 122412 | BRD-A12896037 | MDAMB231 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122436 | BRD-A12896037 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.75 | 0.06 |
| 122468 | BRD-A12896037 | THP1 | 10 uM | 24 h | 0.24 | 1.0 | 0.11 | 0.0 | 0.0 | 0.0 |
| 122513 | BRD-A12896037 | YAPC | 1.11 uM | 24 h | -0.31 | -1.3 | 0.81 | -0.35 | -1.18 | 1.14 |
| 130586 | BRD-A12896037 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.72 | 0.04 |
| 130619 | BRD-A12896037 | HEK293 | 0.08 uM | 24 h | -0.29 | -1.22 | 0.61 | 0.24 | 0.86 | 0.16 |
| 130660 | BRD-A12896037 | HELA | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.86 | 0.22 |
| 130702 | BRD-A12896037 | HT29 | 2.22 uM | 24 h | 0.17 | 0.72 | 0.0 | 0.3 | 1.05 | 0.57 |
| 130737 | BRD-A12896037 | MCF10A | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |