CMap Candidate Details
Structure:
| CMap ID: | C01291 |
| Pert ID: | BRD-K17498618 |
| Compound Name: | cisatracurium |
| Targets: | CHRNA2 |
| MoA: | acetylcholine receptor antagonist |
| SMILES: | COc1ccc(C[C@@H]2c3cc(OC)c(OC)cc3CC[N@+]2(C)CCC(=O)OCCCCCOC(=O)CC[N@@+]2(C)CCc3cc(OC)c(OC)cc3[C@H]2Cc2ccc(OC)c(OC)c2)cc1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120250 | BRD-K17498618 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.91 | 0.24 |
| 120289 | BRD-K17498618 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120322 | BRD-K17498618 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.16 | 1.08 |
| 120349 | BRD-K17498618 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.71 | 0.03 |
| 120382 | BRD-K17498618 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120413 | BRD-K17498618 | MCF??7.00 | 10 uM | 24 h | 0.24 | 0.99 | 0.09 | 0.25 | 0.88 | 0.19 |
| 120485 | BRD-K17498618 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128975 | BRD-K17498618 | PC3 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |