CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01293
Pert ID:	BRD-A47598013
Compound Name:	citalopram
Targets:	SLC6A2\|SLC6A4
MoA:	selective serotonin reuptake inhibitor (SSRI)
SMILES:	CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1448	BRD-A47598013	NPC	6.66 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7548	BRD-A47598013	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
19387	BRD-A47598013	A549	10 uM	6 h	0.23	0.95	0.06	-0.37	-1.24	1.35
19552	BRD-A47598013	HA1E	10 uM	6 h	0.16	0.68	0.0	0.0	0.0	0.0
20202	BRD-A47598013	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
20835	BRD-A47598013	MCF??7.00	10 uM	24 h	0.21	0.86	0.01	0.25	0.9	0.21
25297	BRD-A47598013	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91467	BRD-A47598013	HUH7	10 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
100183	BRD-A47598013	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
124568	BRD-A47598013	A375	10 uM	24 h	0.0	0.0	0.0	0.36	1.28	1.42
124679	BRD-A47598013	HT29	0.04 uM	24 h	0.28	1.17	0.37	0.0	0.0	0.0
124780	BRD-A47598013	MDAMB231	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124825	BRD-A47598013	PC3	0.04 uM	24 h	0.25	1.05	0.17	0.25	0.89	0.2
124869	BRD-A47598013	THP1	3.33 uM	24 h	-0.28	-1.18	0.5	0.0	0.0	0.0
132739	BRD-A47598013	HEK293	0.01 uM	24 h	0.0	0.0	0.0	-0.36	-1.2	1.19
132780	BRD-A47598013	HELA	0.01 uM	24 h	0.0	0.0	0.0	0.43	1.52	2.29
132825	BRD-A47598013	JURKAT	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132857	BRD-A47598013	MCF10A	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132942	BRD-A47598013	YAPC	0.25 uM	24 h	-0.21	-0.86	0.02	0.0	0.0	0.0

Summary