CMap Candidate Details
Structure:
| CMap ID: | C01305 |
| Pert ID: | BRD-K49668410 |
| Compound Name: | clarithromycin |
| Targets: | CYP3A4 |
| MoA: | bacterial 50S ribosomal subunit inhibitor |
| SMILES: | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@](C)(C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O)OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24448 | BRD-K49668410 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24675 | BRD-K49668410 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.98 | 0.36 |
| 24783 | BRD-K49668410 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24916 | BRD-K49668410 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25251 | BRD-K49668410 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25381 | BRD-K49668410 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 52171 | BRD-K49668410 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91469 | BRD-K49668410 | HUH7 | 4 uM | 72 h | -0.26 | -1.09 | 0.33 | 0.25 | 0.88 | 0.18 |