CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01315
Pert ID:	BRD-A93964801
Compound Name:	clinafloxacin
Targets:
MoA:	bacterial DNA gyrase inhibitor
SMILES:	NC1CCN(C1)c1c(F)cc2c(c1Cl)n(cc(C(O)=O)c2=O)C1CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
91473	BRD-A93964801	HUH7	10 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
128378	BRD-A93964801	A549	1.11 uM	24 h	0.0	0.0	0.0	-0.19	-0.64	0.01
128433	BRD-A93964801	HEK293	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128503	BRD-A93964801	HT29	10 uM	24 h	0.0	0.0	0.0	-0.37	-1.23	1.28
128543	BRD-A93964801	JURKAT	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128635	BRD-A93964801	MDAMB231	10 uM	24 h	-0.22	-0.92	0.06	0.27	0.96	0.33
128715	BRD-A93964801	THP1	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128763	BRD-A93964801	YAPC	10 uM	24 h	0.31	1.28	0.64	0.38	1.36	1.72
136175	BRD-A93964801	A375	2.22 uM	24 h	0.0	0.0	0.0	0.33	1.16	0.91
136220	BRD-A93964801	HA1E	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136260	BRD-A93964801	HELA	0.03 uM	24 h	-0.26	-1.07	0.28	0.27	0.95	0.31
136309	BRD-A93964801	MCF10A	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136340	BRD-A93964801	MCF??7.00	0.03 uM	24 h	0.0	0.0	0.0	0.35	1.25	1.28
136363	BRD-A93964801	PC3	2.22 uM	24 h	0.23	0.98	0.09	0.0	0.0	0.0

Summary