Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C01319
Pert ID: BRD-A90625545
Compound Name: clinofibrate
Targets: LPL
MoA: lipase clearing factor inhibitor
SMILES: CCC(C)(Oc1ccc(cc1)C1(CCCCC1)c1ccc(OC(C)(CC)C(O)=O)cc1)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127735 BRD-A90625545 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127778 BRD-A90625545 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127818 BRD-A90625545 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127858 BRD-A90625545 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127932 BRD-A90625545 HUVEC 1.11 uM 24 h -0.26 -1.07 0.28 -0.28 -0.93 0.34
127986 BRD-A90625545 MCF10A 10 uM 24 h -0.25 -1.06 0.26 0.0 0.0 0.0
128046 BRD-A90625545 PC3 0.04 uM 24 h -0.24 -1.0 0.14 0.0 0.0 0.0
135559 BRD-A90625545 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.68
135606 BRD-A90625545 HT29 0.74 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
135650 BRD-A90625545 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135691 BRD-A90625545 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
135740 BRD-A90625545 YAPC 0.25 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).