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CMap Candidate Details

Structure:
CMap ID: C01331
Pert ID: BRD-K45252063
Compound Name: clofibrate
Targets: LPL|PPARA
MoA: PPAR receptor agonist
SMILES: CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5636 BRD-K45252063 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6551 BRD-K45252063 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37667 BRD-K45252063 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37908 BRD-K45252063 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.14
38492 BRD-K45252063 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38730 BRD-K45252063 PHH 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
52165 BRD-K45252063 MCF??7.00 10 uM 6 h 0.24 1.01 0.11 0.0 0.0 0.0
91177 BRD-K45252063 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
125298 BRD-K45252063 HEK293 0.04 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
125350 BRD-K45252063 HELA 10 uM 24 h 0.24 1.0 0.1 -0.34 -1.15 1.05
125370 BRD-K45252063 HT29 10 uM 24 h -0.17 -0.72 0.0 0.28 0.98 0.36
125470 BRD-K45252063 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
125487 BRD-K45252063 PC3 0.37 uM 24 h -0.28 -1.18 0.5 -0.4 -1.35 2.02
133332 BRD-K45252063 A375 0.25 uM 24 h -0.19 -0.78 0.0 0.35 1.23 1.21
133357 BRD-K45252063 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133381 BRD-K45252063 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133474 BRD-K45252063 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133505 BRD-K45252063 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133598 BRD-K45252063 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133620 BRD-K45252063 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).