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CMap Candidate Details

Structure:
CMap ID: C01379
Pert ID: BRD-K61195623
Compound Name: combretastatin-A-4
Targets:
MoA: tubulin polymerization inhibitor
SMILES: COc1ccc(cc1O)\C=C/c1cc(OC)c(OC)c(OC)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123816 BRD-K61195623 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123857 BRD-K61195623 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123926 BRD-K61195623 HEK293 3.33 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.56
124028 BRD-K61195623 JURKAT 10 uM 24 h -0.16 -0.68 0.0 -0.26 -0.87 0.23
124079 BRD-K61195623 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124157 BRD-K61195623 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124209 BRD-K61195623 THP1 0.37 uM 24 h -0.28 -1.15 0.43 -0.28 -0.93 0.34
124262 BRD-K61195623 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132180 BRD-K61195623 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.36
132212 BRD-K61195623 HELA 0.01 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
132244 BRD-K61195623 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
132267 BRD-K61195623 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.8
132281 BRD-K61195623 MDAMB231 0.08 uM 24 h -0.17 -0.69 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).