CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01383
Pert ID:	BRD-K37385792
Compound Name:	conivaptan
Targets:	AVPR1A\|AVPR2
MoA:	vasopressin receptor antagonist
SMILES:	Cc1nc2CCN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c3ccccc3-c2[nH]1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
96624	BRD-K37385792	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123256	BRD-K37385792	A549	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123269	BRD-K37385792	HA1E	10 uM	24 h	0.24	0.99	0.1	0.23	0.81	0.09
123329	BRD-K37385792	HT29	10 uM	24 h	0.18	0.75	0.0	0.0	0.0	0.0
123387	BRD-K37385792	MDAMB231	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123409	BRD-K37385792	PC3	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123444	BRD-K37385792	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123478	BRD-K37385792	YAPC	10 uM	24 h	0.0	0.0	0.0	0.37	1.3	1.49
131607	BRD-K37385792	HEK293	0.74 uM	24 h	-0.22	-0.94	0.07	0.19	0.66	0.01
131648	BRD-K37385792	HELA	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131700	BRD-K37385792	HUVEC	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131753	BRD-K37385792	JURKAT	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131808	BRD-K37385792	MCF10A	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131837	BRD-K37385792	MCF??7.00	0.01 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.39

Summary