CMap Candidate Details
Structure:
| CMap ID: | C01384 |
| Pert ID: | BRD-K24666289 |
| Compound Name: | copanlisib |
| Targets: | PIK3CA|PIK3CB|PIK3CD|PIK3CG |
| MoA: | PI3K inhibitor |
| SMILES: | COc1c(OCCCN2CCOCC2)ccc2C3=NCCN3C(NC(=O)c3cnc(N)nc3)=Nc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 482 | BRD-K24666289 | BJAB | 10 uM | 24 h | 0.24 | 0.98 | 0.09 | 0.0 | 0.0 | 0.0 |
| 549 | BRD-K24666289 | HBL1 | 10 uM | 4 h | 0.0 | 0.0 | 0.0 | 0.41 | 1.44 | 2.21 |
| 590 | BRD-K24666289 | K562 | 10 uM | 4 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.27 | 1.44 |
| 620 | BRD-K24666289 | KMS34 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 665 | BRD-K24666289 | MINO | 2.5 uM | 24 h | -0.23 | -0.98 | 0.12 | 0.28 | 1.0 | 0.42 |
| 713 | BRD-K24666289 | NALM6 | 2.5 uM | 24 h | 0.18 | 0.74 | 0.0 | 0.0 | 0.0 | 0.0 |
| 754 | BRD-K24666289 | OCILY19 | 0.66 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 803 | BRD-K24666289 | OCILY3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 854 | BRD-K24666289 | SKMEL5 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 900 | BRD-K24666289 | THP1 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 955 | BRD-K24666289 | TMD8 | 10 uM | 4 h | 0.23 | 0.94 | 0.06 | 0.17 | 0.6 | 0.0 |