CMap Candidate Details
Structure:
| CMap ID: | C01389 |
| Pert ID: | BRD-K73589401 |
| Compound Name: | corticosterone |
| Targets: | HSD11B1|NCOA1|NR3C2 |
| MoA: | mineralocorticoid receptor agonist |
| SMILES: | C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 21957 | BRD-K73589401 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 22336 | BRD-K73589401 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.19 | 1.16 |
| 22558 | BRD-K73589401 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 22841 | BRD-K73589401 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 23142 | BRD-K73589401 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.75 |
| 23431 | BRD-K73589401 | HT29 | 10 uM | 6 h | -0.21 | -0.87 | 0.02 | -0.38 | -1.28 | 1.45 |
| 23632 | BRD-K73589401 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24036 | BRD-K73589401 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24344 | BRD-K73589401 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.92 |
| 91199 | BRD-K73589401 | HUH7 | 10 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99448 | BRD-K73589401 | U2OS | 10 uM | 6 h | -0.2 | -0.85 | 0.01 | -0.28 | -0.93 | 0.35 |