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CMap Candidate Details

Structure:
CMap ID: C01406
Pert ID: BRD-K76908866
Compound Name: CP-724714
Targets: ERBB2
MoA: EGFR inhibitor; protein tyrosine kinase inhibitor
SMILES: COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
30111 BRD-K76908866 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30551 BRD-K76908866 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
31134 BRD-K76908866 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31447 BRD-K76908866 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
32237 BRD-K76908866 NEU 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
32526 BRD-K76908866 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33135 BRD-K76908866 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33355 BRD-K76908866 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91523 BRD-K76908866 BT20 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91727 BRD-K76908866 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91977 BRD-K76908866 A375 10 uM 24 h -0.27 -1.13 0.41 -0.26 -0.88 0.25
92152 BRD-K76908866 HS578T 1.11 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92226 BRD-K76908866 MCF10A 1.11 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92267 BRD-K76908866 MCF??7.00 1.11 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92279 BRD-K76908866 MDAMB231 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126415 BRD-K76908866 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126487 BRD-K76908866 HT29 10 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.05
126588 BRD-K76908866 YAPC 10 uM 24 h 0.0 0.0 0.0 0.21 0.76 0.05
134387 BRD-K76908866 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134417 BRD-K76908866 HELA 2.22 uM 24 h -0.17 -0.69 0.0 -0.42 -1.41 2.02
134482 BRD-K76908866 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134615 BRD-K76908866 PC3 0.08 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).