CMap Candidate Details
Structure:
| CMap ID: | C01416 |
| Pert ID: | BRD-K11073688 |
| Compound Name: | CPI-1189 |
| Targets: | TNF |
| MoA: | tumor necrosis factor release inhibitor |
| SMILES: | CC(=O)Nc1ccc(cc1)C(=O)NC(C)(C)C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121168 | BRD-K11073688 | A375 | 1.11 uM | 24 h | -0.27 | -1.12 | 0.39 | 0.24 | 0.84 | 0.12 |
| 121204 | BRD-K11073688 | A549 | 1.11 uM | 24 h | -0.22 | -0.92 | 0.06 | 0.0 | 0.0 | 0.0 |
| 121295 | BRD-K11073688 | MCF??7.00 | 0.04 uM | 24 h | 0.2 | 0.85 | 0.01 | -0.21 | -0.71 | 0.03 |
| 121330 | BRD-K11073688 | PC3 | 1.11 uM | 24 h | -0.28 | -1.16 | 0.48 | 0.0 | 0.0 | 0.0 |
| 129257 | BRD-K11073688 | HA1E | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129283 | BRD-K11073688 | HELA | 0.01 uM | 3 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.95 |
| 129317 | BRD-K11073688 | HT29 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129389 | BRD-K11073688 | YAPC | 0.74 uM | 24 h | 0.22 | 0.91 | 0.04 | 0.0 | 0.0 | 0.0 |