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CMap Candidate Details

Structure:
CMap ID: C01434
Pert ID: BRD-M89827113
Compound Name: cromakalim
Targets: KCNJ8
MoA:
SMILES: CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N1CCCC1=O)C#N.CC1(C)Oc2ccc(cc2[C@@H]([C@H]1O)N1CCCC1=O)C#N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96618 BRD-M89827113 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.22
127777 BRD-M89827113 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127817 BRD-M89827113 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127856 BRD-M89827113 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.11
127930 BRD-M89827113 HUVEC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
127984 BRD-M89827113 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128073 BRD-M89827113 YAPC 10 uM 24 h 0.22 0.9 0.03 -0.28 -0.94 0.38
135557 BRD-M89827113 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135605 BRD-M89827113 HT29 0.74 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
135648 BRD-M89827113 JURKAT 0.25 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
135690 BRD-M89827113 MCF??7.00 2.22 uM 24 h 0.29 1.2 0.43 -0.26 -0.88 0.25
135716 BRD-M89827113 PC3 0.03 uM 24 h 0.28 1.15 0.33 -0.31 -1.03 0.65
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).