CMap Candidate Details
Structure:
CMap ID: | C01455 |
Pert ID: | BRD-K90777969 |
Compound Name: | cutamesine |
Targets: | SIGMAR1 |
MoA: | sigma receptor agonist |
SMILES: | COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC |
InchiKey: | |
Compound Aliases: |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
127739 | BRD-K90777969 | A375 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
127782 | BRD-K90777969 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
127862 | BRD-K90777969 | HEK293 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.9 |
127936 | BRD-K90777969 | HUVEC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
127989 | BRD-K90777969 | MCF10A | 3.33 uM | 24 h | 0.22 | 0.9 | 0.02 | -0.27 | -0.92 | 0.33 |
128075 | BRD-K90777969 | YAPC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.13 | 0.99 |
135526 | BRD-K90777969 | HA1E | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
135563 | BRD-K90777969 | HELA | 0.01 uM | 24 h | 0.29 | 1.21 | 0.45 | 0.0 | 0.0 | 0.0 |
135610 | BRD-K90777969 | HT29 | 0.08 uM | 24 h | -0.21 | -0.89 | 0.04 | 0.0 | 0.0 | 0.0 |
135654 | BRD-K90777969 | JURKAT | 0.03 uM | 24 h | -0.21 | -0.89 | 0.04 | -0.3 | -1.0 | 0.52 |
135693 | BRD-K90777969 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
135717 | BRD-K90777969 | PC3 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |