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CMap Candidate Details

Structure:
CMap ID: C01475
Pert ID: BRD-A77291778
Compound Name: cyclopentolate
Targets: CHRM1
MoA: acetylcholine receptor antagonist
SMILES: CN(C)CCOC(=O)C(c1ccccc1)C1(O)CCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5166 BRD-A77291778 A375 10 uM 6 h -0.17 -0.69 0.0 0.0 0.0 0.0
5281 BRD-A77291778 HA1E 10 uM 24 h 0.27 1.12 0.27 -0.33 -1.12 0.93
5736 BRD-A77291778 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6150 BRD-A77291778 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6489 BRD-A77291778 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42032 BRD-A77291778 A549 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
42235 BRD-A77291778 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42576 BRD-A77291778 HEPG2 10 uM 6 h -0.19 -0.79 0.0 0.0 0.0 0.0
42881 BRD-A77291778 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43434 BRD-A77291778 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.88
44028 BRD-A77291778 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52051 BRD-A77291778 MCF??7.00 10 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
100328 BRD-A77291778 U2OS 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.51
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).