CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01476
Pert ID:	BRD-A09722536
Compound Name:	cyclophosphamide
Targets:	CYP2A6\|CYP2B6\|CYP2C18\|CYP2C19\|CYP2C8\|CYP2C9\|CYP2D6\|CYP3A4\|CYP3A5\|CYP3A7
MoA:	DNA alkylating agent
SMILES:	ClCCN(CCCl)P1(=O)NCCCO1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
50799	BRD-A09722536	PC3	10 uM	24 h	0.0	0.0	0.0	0.35	1.25	1.28
50972	BRD-A09722536	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
52074	BRD-A09722536	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
52370	BRD-A09722536	HA1E	20 uM	6 h	-0.28	-1.15	0.44	0.23	0.82	0.1
53275	BRD-A09722536	MCF10A	12 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
87319	BRD-A09722536	BJAB	0.01 uM	6 h	0.0	0.0	0.0	-0.37	-1.23	1.28
87344	BRD-A09722536	HBL1	0.66 uM	24 h	0.0	0.0	0.0	0.24	0.86	0.16
87395	BRD-A09722536	K562	0.66 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
87442	BRD-A09722536	KMS34	10 uM	24 h	0.0	0.0	0.0	0.24	0.83	0.12
87517	BRD-A09722536	MINO	0.66 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
87546	BRD-A09722536	NALM6	2.5 uM	24 h	0.0	0.0	0.0	0.33	1.15	0.9
87597	BRD-A09722536	OCILY10	0.01 uM	24 h	0.0	0.0	0.0	-0.38	-1.29	1.57
87646	BRD-A09722536	OCILY19	0.125 uM	24 h	0.0	0.0	0.0	0.29	1.02	0.48
87698	BRD-A09722536	OCILY3	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
87746	BRD-A09722536	SKMEL5	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
87799	BRD-A09722536	THP1	10 uM	3 h	-0.28	-1.16	0.46	0.0	0.0	0.0
87845	BRD-A09722536	TMD8	0.04 uM	3 h	0.0	0.0	0.0	0.0	0.0	0.0
91203	BRD-A09722536	HUH7	12.5 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
96075	BRD-A09722536	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117346	BRD-A09722536	A375	0.37 uM	24 h	-0.26	-1.1	0.35	0.23	0.81	0.09
117470	BRD-A09722536	HCC515	0.37 uM	24 h	0.19	0.78	0.0	-0.28	-0.94	0.37
117517	BRD-A09722536	HEPG2	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117560	BRD-A09722536	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary